Salvage brachytherapy for locally recurrent prostate cancer after external beam radiotherapy

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Salvage brachytherapy for locally recurrent prostate cancer after external beam radiotherapy

External beam radiotherapy (EBRT) is a standard treatment for prostate cancer. Despite the development of novel radiotherapy techniques such as intensity-modulated conformal radiotherapy, the risk of local recurrence after EBRT has not been obviated. Various local treatment options (including salvage prostatectomy, brachytherapy, cryotherapy, and high-intensity focused ultrasound [HIFU]) have b...

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Salvage brachytherapy after external-beam irradiation for prostate cancer.

The options available for patients with recurrent prostate cancer are limited. Men who have failed external-beam irradiation as the primary treatment are rarely considered for potentially curative salvage therapy. Traditionally, only palliative treatments have been offered with hormonal intervention or simple observation. A significant percentage of these patients have only locally recurrent ca...

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Salvage External Beam Radiotherapy for Prostate Cancer After Radical Prostatectomy

Prostate cancer is the second most common cause of cancer death in American men, with 192,289 new cases and 27,360 deaths expected in 2009.[1] While radical prostatectomy provides excellent control for clinically localized disease, approximately one-third of patients undergoing surgery will have positive surgical margins and another 9% will have seminal vesicle invasion.[2-5] Around one-third o...

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A Phase II study of salvage high-dose-rate brachytherapy for the treatment of locally recurrent prostate cancer after definitive external beam radiotherapy

PURPOSE We report the toxicity and biochemical tumor control outcome of a prospective Phase II study using high-dose-rate brachytherapy (HDR) alone as a salvage therapy for recurrent disease after external beam radiotherapy (EBRT). METHODS Forty-two patients with biopsy-proven recurrence were enrolled on a Phase II study of salvage HDR monotherapy using iridium-192. Median pretreatment EBRT d...

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Salvage low-dose-rate 125I partial prostate brachytherapy after dose-escalated external beam radiotherapy

PURPOSE To report outcomes on 5 patients treated with salvage partial low-dose-rate (LDR) 125-iodine ((125)I) permanent prostate seed brachytherapy (BT) for biopsy-proven locally persistent prostate cancer, following failure of dose-escalated external beam radiotherapy (EBRT). MATERIAL AND METHODS A retrospective review of the Fox Chase Cancer Center prostate cancer database identified five p...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2015

ISSN: 1008-682X

DOI: 10.4103/1008-682x.151391